The following information\u00a0consist of\u00a0the most documented underlying issues that result in joint conttractions. To really move toward an actual treatment or correction of the issues we must query doctors to find out which of the followings affect our children and what can be done to improve thier condition.<\/p>\n
Abnormalities of the Muscle Structure or Function<\/strong> Abnormalities of the Nerves That Connect<\/strong> Abnormalities of Connective Tissue<\/strong> The following information\u00a0consist of\u00a0the most documented underlying issues that result in joint conttractions. To really move toward an actual treatment or correction of the issues we must query doctors to find out which of the followings affect our children and … Continue reading
\nThese are called myopathic processes. In these individuals, muscles form
\nabnormally or develop normally but do not function properly. In most cases,
\nthe cause of this lack of muscle development or abnormality in muscle function
\nis not known. Some suspected causes include muscle disease such as
\ncongenital muscular dystrophies, mitochondrial disturbances such that the
\nmuscles do not have enough energy to function normally, and abnormalities
\nof the biochemistry of the muscle.<\/p>\n
\n to the Muscles<\/strong>
\nThese are called neuropathic processes. There may have been a failure of the
\nnerves to form, failure to mature, or failure to function properly. The problem
\ncan be in the brain, in the spinal cord, or in the peripheral nerves and
\ntheir connection to the muscle. When the central nervous system and spinal
\ncord are malformed, as in individuals with neural tube defects (defects in the
\nclosing of the spine), there may be very severe lack of movement. Failure of
\nneurons to mature or myelinate (formation of the insulation of the nerves)
\nproperly can also lead to lack of normal movement. Arthrogryposis due to
\nabnormalities in the development and function of the central nervous system
\nis often accompanied by structural abnormalities that can be seen on imaging
\nstudies or if nerve tissue is examined carefully at autopsy.<\/p>\n
\nIn this type of problem, the tendons, bones, joint, or joint lining develop
\nabnormally in such a way that normal movement cannot occur during fetal
\ndevelopment and contractures are present at birth. Examples of abnormal
\nconnective tissue are seen in diastrophic dysplasia (a dwarfing condition
\nwith clubbed feet and hands) or when there are abnormal tendon attachments.
\nThe tendons may have developed appropriately but may not have
\nattached to the proper place around the joint or on the bone. If this happens,
\nnormal movement of the joint may not occur during fetal life, leading
\nto contractures at birth. This is the case in some forms of distal arthrogryposis
\n(Hall et al., 1982a).<\/p>\n","protected":false},"excerpt":{"rendered":"